Discovering the relationship between estrogen levels and the risk of death from Covid-19

Doctors from the University of Southampton in the UK have discovered that the female sex hormone estrogen affects survival from Covid-19.

On average, men have a higher risk of contracting COVID-19 and more likely to die from the disease. In previous studies, scientists have attributed this to differences in hormone levels – in particular, younger women with higher levels of estrogen are less likely to develop complications from COVID-19.

The study authors collected information on nearly 2 million women over 18, of whom 5,451 had COVID-19.

Those who at the time of illness were on hormone replacement therapy, which includes estrogen-containing drugs, or took oral contraceptives with it, had a 22% lower risk of death.

The researchers concluded, “This study supports the theory that estrogen may provide some protection from severe COVID-19.”

What remains is what estrogen levels need to be in order to protect against infection as much as possible, and whether hormone therapy will be effective for men with COVID-19.

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