Wales vs France live: Latest score and updates as struggling hosts face daunting test against Six Nations favourites

France have been forced to name a new-look centre pairing for their Six Nations clash with Wales after both Yoram Moefana and Nicolas Depoortere were ruled out by injury.

Fabien Galthie has again prioritised club cohesion with 20-year-old Pau centre Fabien Brau-Boirie set for a debut alongside Emilien Gailleton, who has won 11 caps.

Tandy swaps props with Rhys Carre and Tomas Francis promoted from the bench as Nicky Smith and Archie Griffin take replacement roles, while Joe Hawkins is preferred to Ben Thomas at inside centre, and will partner clubmate Eddie James.

Wales face another daunting challenge as they welcome the tournament favourites to the Principality Stadium, having conceded an average of nearly 58 points across their last three outings.

The second round of the Six Nations concludes in Cardiff as Wales face up to another daunting task with France in town. The woes continue for Welsh rugby with empty seats expected today at the Principality Stadium after an opening drubbing by England – and another sizeable scoreline could be on the cards against the tournament favourites.

Can Steve Tandy’s side spring an almighty shock? We’ll find out from 3.10pm GMT.