Barbra Streisand grills Melissa McCarthy about Ozempic use in Instagram comments section leaving fans GOBSMACKED

Barbra Streisand left fans reeling after publicly grilling Melissa McCarthy about Ozempic on Instagram on Monday.

McCarthy, 53, posted an image of herself and pal Adam Shankman, 59, in Los Angeles on Sunday at CTG’s The Gala 2024 at the Ahmanson Theatre.

The comedian – whose weight has fluctuated over the years – showcased her newly slimmed down figure in a stylish mint dress and blazer. 

‘Pastels only to honor the incredible @matthewbourne13 at the @ctgla gala last night with this fella @adamshankman !!’ the Oscar-nominated actress captioned the image. ‘Thiiiiis much closer to my dream of dancing on stage.’

Streisand, 82, responded in the comment thread with the question, ‘Give him my regards did you take Ozempic?’

The EGOT-winning entertainer was quickly at the receiving end of dozens of responses calling out the nature of her inquiry.

‘Wow really!’ one user said. ‘What happened to not taking about Bodies! As a mother of a daughter that’s not ok we as women need to not focus on appearance.’

Said another user to Streisand, ‘I’m so totally taken aback that you could ask her that on Social Media for all to see? I love and adore you, truly, but that disappointed me.’

Another user said, ‘Whether she did or did not is no one else’s business,’ while others described the line of questioning as ‘rude,’ ‘nasty,’ ‘disgusting and disrespectful.’

One user said Streisand’s remark was indicative of a vapid mentality in Hollywood: ‘Movie stars will never stop focusing on appearance.’

Another user said that McCarthy ‘looks healthy, no matter how she got there’ and that they were ‘surprised at the lack of respect’ Streisand showed with her question.

‘How about just being healthy for the sake of being healthy?’ the user added.

Another user asked Streisand, ‘Did you actually just have the audacity to ask her that?! Especially right out here on social media!!!’

One user questioned the possibility someone was posting under Streisand’s handle, saying that ‘this cannot possibly be the real Babs.’

Another suggested Streisand ‘meant this to be a private message.’

Said one user: ‘It doesn’t sound like something Barbra would say.’ 

Not everyone was offended, as one user said they were ‘in shock with that comment’ with a pair of hysterical laughing emojis.

One user opted to tell The Prince of Tides star explicitly: ‘BARBRA YOU CANT JUST ASK IF SOMEONE IS ON OZEMPIC HAHAHAHAHA SAVAGE.’ 

Of course, Streisand is not the first to wonder if McCarthy’s transformation is a result of Hollywood’s new favorite weight loss drug. 

For months, fans have speculated if McCarthy was using Ozempic, but she hasn’t publicly confirmed or denied the rumors.

Streisand and McCarthy have past worked together on the song Anything You Can Do for Streisand’s 2016 album Encore: Movie Partners Sing Broadway, a collection of duets that also included collaborations with Hugh Jackman, Alec Baldwin and Jamie Foxx.

McCarthy last June told Entertainment Weekly she initially thought the offer to perform along the legendary entertainer was a practical joke.

McCarthy said of Streisand, ‘She’s really funny,’ adding that her down-to-earth demeanor dispelled expectations the Funny Girl star would have a regal demeanor about her.

‘That’s what I almost wanted,’ McCarthy said. ‘And then, I think when she opened the door she had leggings on and lunch meat in her hand. And I was like, none of this is what I expected.

‘She’s so who she is. And also, when someone who you think you should be curtseying to keeps eating lunch meat, it really kind of levels the playing field. It was really charming. I was like, “You’re really pounding lunch meat.” She’s like, “Yeah.”‘