Health and Wellness

Pesticide warning as study finds link to terrifying motor neurone disease – exposure could raise risk by up to 70%

Exposure to pesticides sprayed on fruits, vegetables and other plants could increase the risk of devastating motor neurone disease by up to 70 per cent, a study has found. 

Those who work with the chemicals, such as farmers, are dramatically more likely to develop amyotrophic lateral sclerosis (ALS) – the most common form of motor neurone disease. 

ALS, which affects around 5,000 Britons, causes nerve cells that control movement to deteriorate.

This leads to a host of life-ruining symptoms like muscle weakness, loss of mobility, speech difficulties and changes to thinking and behaviour – robbing victims of their independence.

Just 20 per cent of ALS patients live for longer than five years. And in many cases, the prognosis is as little as two years.

The cause of the disorder is not yet fully known, but scientists – from the Robert Suave Institute For Research in Quebec, have identified an interesting theory.  

The team reviewed almost 800 studies but used 11 for their analysis, and involved data from more than 2,000 people with ALS or another type of MND.

They found that those who had been exposed to pesticides at work were around 60 per cent more likely to develop ALS than those who had never been exposed.

Farmers and workers exposed to pesticides could be at a 70 per cent higher risk of developing deadly motor neurone disease

But those exposed mostly to herbicides – or weedkiller -had a 70 per cent increased risk.

Pesticides are chemicals used to protect crops by killing or controlling weeds, insects and fungi.

The main types are herbicides, as well as insecticides and fungicides.

Even lower levels of exposure to pesticides of any kind were associated with around double the risk. 

Interestingly, when researchers analysed men and women separately, they discovered the worrying link only applied to men. 

Commenting on the findings in the journal Occupational and Environmental Medicine, the experts urged officials to introduce ‘interventions aimed at reducing exposure during occupational pesticide use.’

The World Health Organisation has branded pesticides ‘intrinsically toxic’ and deemed them ‘among the leading causes of death by self-poisoning’.

Several pesticides are not permitted for use in the UK. 

Insecticide Chlorpyrifos was banned in Britain in 2016 after evidence revealed it can harm the cognitive development of foetuses and young children.

Toxic weedkiller Paraquat was also banned in the UK due to increased risk of Parkinson’s disease.

However, British crops are still sprayed with some pesticides banned by the EU.

These include Dimethomorph, which is typically sprayed on strawberries and onions, Benthiavalicarb, used on potatoes, and Ipconazole, authorised in the UK for barley and wheat seeds.

Experts not involved in the new study have commented on its findings, urging caution.

Dr Johnathan Cooper-Knock, clinical lecturer at the University of Sheffield’s School of Medicine and Population Health, said: ‘The strength of this research is the use of data from eleven different studies and more than 2000 MND patients; the findings are interesting and should lead to further work.

‘However, this is a retrospective analysis which uses indirect measurements of pesticide exposure and it is therefore almost impossible to know whether the effect seen is mediated by the pesticide exposure or some unseen factor which may be correlated with pesticide exposure.’

Dr Nick Cole, head of research at MND Association UK, said: ‘This is a systematic review and meta-analysis, meaning it is a review of selected literature and its statistical analysis. 

‘The study cannot establish that pesticides cause MND, only that there is a statistical association in the limited available data… readers should treat the specific percentage increases with caution.’

What is motor neurone disease? 

Motor neurone disease is a rare condition that mainly affects people in their 60s and 70s, but it can affect adults of all ages.

It’s caused by a problem with cells in the brain and nerves called motor neurones. These cells gradually stop working over time. It’s not known why this happens.

Having a close relative with motor neurone disease, or a related condition called frontotemporal dementia, can sometimes mean you’re more likely to get it. But it doesn’t run in families in most cases.

Early symptoms can include weakness in your ankle or leg, like finding it hard to walk upstairs; slurred speech, finding it hard to swallow, a weak grip, and gradual weight loss.

If you have these symptoms, you should see a GP. They will consider other possible conditions and can refer you to a specialist called a neurologist if necessary.

If a close relative has motor neurone disease or frontotemporal dementia and you’re worried you may be at risk of it, they may refer you to a genetic counsellor to talk about your risk and any tests you can have.

Source: NHS UK 

 

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