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Serena Williams, 44, makes stunning tennis return with husband and kids cheering her on at Wimbledon – after using weight-loss jabs to kick-start her comeback

Serena Williams made an emotional return to Wimbledon, competing in the singles draw at a tournament for the first time in four years, in front of her family on Tuesday. 

The 44-year-old icon sealed a remarkable comeback to the sport when she took to Centre Court at Wimbledon to face World No 87 Maya Joint. 

The 23-time Grand Slam champion was calm and collected as she strolled confidently out onto the heart of SW19. 

The crowd inside the iconic court let out a raucous round of applause, wildly cheering the tennis legend. Not that Williams would have heard, sporting a pair of pale pink headphones to drown out the noise and stay in the zone. 

There was no chance she could have missed the rupture of cheers minutes later when she claimed the first point of the match on her opponent’s serve. 

It was tough not to feel for Joint, the echoing cheers making it clear that, even after a four-year hiatus, Williams was still very much the favorite and Joint the underdog.  

Serena Williams made her singles comeback on her return to Wimbledon on Tuesday

The legend was supported by her husband Alexis Ohanian and their two daughters

The legend was supported by her husband Alexis Ohanian and their two daughters 

At just 20 years old, the Australian is part of the new generation of female tennis players who have never before faced Williams on the court. 

Tuesday’s first-round clash marked Williams’ return to SW19 and first singles action for the first time in four years after having publicly stepped away from the sport following the 2022 US Open. 

In the time since she ‘evolved’ away from the sport, Williams welcomed her second daughter, Adira, with Alexis Ohanian, who was in her box to cheer her on. 

The two-year-old defied Wimbledon’s age restrictions for Centre Court to sit alongside her dad and older sister Olympia, eight, and watch her mom compete at SW19 for the first time. 

Wimbledon traditionally enforces an age limit of five and above to attend the show courts. However, exceptions were evidently made for the daughter of a seven-time winner.

Williams’ posse of supporters was rounded out by her sister Venus and new brother-in-law, Italian actor Andrea Preti, whom Venus wed last year. 

The sisters will form a powerful duo later in the week when they team up in the doubles draw, where they have found formidable success in the past, winning six times.  

The All England Club had left one women’s singles wildcard slot conspicuously unclaimed, and on Sunday it was announced that Serena will test herself against the best players in the world – many of whom are less than half her age – at the event she has won seven times.

The 44-year-old began her comeback to tennis – four years after her last professional match – at the Queen’s Club’s HSBC Championships, where she won a round before being forced out by an injury to her partner Victoria Mboko.

Ohanian sat in Williams' box with Adria, two (left), and Olympic, eight, (right)

Ohanian sat in Williams’ box with Adria, two (left), and Olympic, eight, (right) 

Williams' youngest applauds her legendary mom as Ohanian lifts her up in the player's box

Williams’ youngest applauds her legendary mom as Ohanian lifts her up in the player’s box 

Tuesday's first-round clash marks her return to SW19 for the first time in four years

Tuesday’s first-round clash marks her return to SW19 for the first time in four years

Her sister Venus and new brother-in-law, Italian actor Andrea Preti, were also in attendance

Her sister Venus and new brother-in-law, Italian actor Andrea Preti, were also in attendance 

Williams had previously hinted at a potential return to the grass courts after kicking off her competitive tennis comeback in the doubles draw alongside Venus. 

Many will be questioning if the veteran still possesses her titan talent, others may be more focused on the question mark over one particular detail of her preparation -whether Williams has continued to use GLP-1 jabs managed by telehealth company Ro, of which she became a vocal paid spokesperson for last year.

The seven-time Wimbledon champion’s husband Alexis Ohanian sits on the company’s board and was an early investor. As recently as this February Williams, the company’s celebrity face, featured in a Super Bowl advert for the brand and its Zepbound tirzepatide jab, which is also marketed under the name Mounjaro.

Williams, who is said to have lost close to two and a half stone, or 34 pounds (15kg) using the drug, previously called her challenge to lose weight following the birth of her two children ‘the one opponent (she) couldn’t beat’.

It remains unclear as to whether Williams has continued to use the drug, which also treats symptoms of diabetes, with her publicist declining to comment when asked by the Atlantic.

But although GLP-1s are not banned by the World Anti-Doping Agency (WADA), they are one of the drugs under ongoing investigation as to whether they might be classed as performance-enhancing in the future.

Although Williams would be the first athlete to publicly use a GLP-1 if she was still using Zepbound, tennis has an existing relationship with weight-loss jabs, with semaglutide Ozempic a surprising sponsor at last year’s Canadian Open.

Speaking to Professor Olivier Rabin, WADA’s head of science, Daily Mail Sport learned that the organisation’s study into the GLP-1s was extended in 2026.

Proud Venus appeared to film her sister's blockbuster entrance onto Centre Court

Proud Venus appeared to film her sister’s blockbuster entrance onto Centre Court 

Williams has previously been outspoken on her use of weight-loss medication through her role as an ambassador for Ro

Williams has previously been outspoken on her use of weight-loss medication through her role as an ambassador for Ro

Williams made her return to tennis and dominated at the Queen's Club at the start of the month

Williams made her return to tennis and dominated at the Queen’s Club at the start of the month

‘The WADA List Expert Advisory Group has discussed their status, as well as other substances of the same class,’ the statement shared with the Athletic from the agency in June read.

‘Semaglutide and tirzepatide were added to the Monitoring Program to track patterns of use in sports in and out of competition. The Monitoring Program includes substances which are not on the Prohibited List, but that WADA wishes to monitor in order to detect potential patterns of misuse in sport.’

Before being able to announce her comeback, Williams had to return to the anti-doping testing pool. 

However, the tennis legend took aim at the regulations when asked about returning to the pool on Sunday. 

‘It’s grueling. They changed the rules now. I didn’t know some of the rules. So apparently if you miss a test outside of your window, it still counts as missed. I’m like, I guess I can’t go pick up my kids,’ said the seven-time Wimbledon champion, a mother of two.

‘It’s unprofessional. I hate it. I think it’s necessary, but I think a lot of the stuff, if I want to go places outside of my window, I should be able to go without having it count as a missed test.’

Players are required by the International Tennis Integrity Agency to provide their daily ‘whereabouts’ for no-notice testing.

Williams described it as ‘unreasonable.’

‘That was a big reason why I didn’t want to come back either,’ she said, ‘because it’s just so hard. I mean, my life is busy, I run a company, I run a VC company, I travel the world. I have children. It’s like I could be in so many different cities so many different times.’

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